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Results Found: 6
  • Sarcoma (TCGA, PanCancer Atlas)

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 255 sarcomas from 255 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information about mutated genes,...

    Subject
    DNA Mutational Analysis
    Fibromatosis, Aggressive
    Fibrosarcoma
    Histiocytoma, Malignant Fibrous
    Leiomyosarcoma
    Liposarcoma
    Nerve Sheath Neoplasms
    Neurofibroma
    Sarcoma
    Sarcoma, Synovial
    Access Rights
    Free to All
  • Sarcoma (TCGA, Firehose Legacy)

    Description

    TCGA Sarcoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 200 carcinomas from 200 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information about mutated...

    Subject
    DNA Mutational Analysis
    Fibromatosis, Aggressive
    Fibrosarcoma
    Histiocytoma, Malignant Fibrous
    Leiomyosarcoma
    Liposarcoma
    Nerve Sheath Neoplasms
    Neurofibroma
    Sarcoma
    Sarcoma, Synovial
    Access Rights
    Free to All
  • The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [ChIP-seq]

    Authors
    Banito, Ana Cristina Tome Moita
    Lowe, Scott W.
    Socci, Nicholas D.
    Description

    From GEO Summary and overall design: Gene fusions arising from chromosomal translocations are key oncogenic drivers in soft tissue sarcomas but little is known about how they exert their oncogenic effects. Our study explores the molecular mechanisms by which the SS18-SSX fusion oncoprotein subverts epigenetic mechanisms of gene regulation to drive synovial sarcoma. Using functional genomics, we identify...

    Subject
    Gene Expression
    Sarcoma, Synovial
    Access Rights
    Free to All
  • The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq]

    Authors
    Banito, Ana Cristina Tome Moita
    Lowe, Scott W.
    Socci, Nicholas D.
    Description

    From GEO Summary and overall design: Gene fusions arising from chromosomal translocations are key oncogenic drivers in soft tissue sarcomas but little is known about how they exert their oncogenic effects. Our study explores the molecular mechanisms by which the SS18-SSX fusion oncoprotein subverts epigenetic mechanisms of gene regulation to drive synovial sarcoma. Using functional genomics, we identify...

    Subject
    Gene Expression
    Sarcoma, Synovial
    Access Rights
    Free to All
  • The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [ATAC-seq]

    Authors
    Banito, Ana Cristina Tome Moita
    Lowe, Scott W.
    Socci, Nicholas D.
    Description

    From GEO Summary and overall design: Gene fusions arising from chromosomal translocations are key oncogenic drivers in soft tissue sarcomas but little is known about how they exert their oncogenic effects. Our study explores the molecular mechanisms by which the SS18-SSX fusion oncoprotein subverts epigenetic mechanisms of gene regulation to drive synovial sarcoma. Using functional genomics, we identify...

    Subject
    Gene Expression
    Sarcoma, Synovial
    Access Rights
    Free to All
  • Adult Soft Tissue Sarcomas (TCGA, Cell 2017): Whole-exome sequencing of 206 Adult Soft Tissue Sarcoma tumor/normal pairs.

    Description

    This dataset contains the summary data visualizations and clinical data from Whole-exome sequencing of 206 Adult Soft Tissue Sarcoma tumor/normal pairs. from 206 patients. Clinical data includes: Cancer Type, Mutation Count, Fraction Genome Altered, Demographic Information, Adjuvant Postoperative Pharmaceutical Therapy Administered Indicator, AMP 12q15 CDK4, AMP 12q15 DDIT3, AMP 12q15 FRS2, AMP 12q15...

    Subject
    Histiocytoma, Malignant Fibrous
    Leiomyosarcoma
    Liposarcoma
    Lymphoma, Non-Hodgkin
    Neurofibrosarcoma
    Sarcoma
    Sarcoma, Synovial
    Access Rights
    Free to All